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On-line glucose monitoring by near infrared spectroscopy during the scale up steps of mammalian cell cultivation process development

NIR spectroscopy is a non-destructive tool for in-situ, on-line bioprocess monitoring. One of its most frequent applications is the determination of metabolites during cultivation, especially glucose. Previous studies have usually investigated the applicability of Near Infrared (NIR) spectroscopy at...

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Detalles Bibliográficos
Autores principales: Kozma, Bence, Salgó, András, Gergely, Szilveszter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527534/
https://www.ncbi.nlm.nih.gov/pubmed/30806782
http://dx.doi.org/10.1007/s00449-019-02091-z