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A gapmer antisense oligonucleotide targeting SRRM4 is a novel therapeutic medicine for lung cancer

Small cell lung cancer (SCLC) is the most aggressive neuroendocrine phenotype of the deadliest human lung cancers. However the therapeutic landscape for SCLC has not changed in over 30 years. Effective treatment and prognosis are needed to combat this aggressive cancer. Herein we report that Ser/Arg...

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Detalles Bibliográficos
Autores principales: Shimojo, Masahito, Kasahara, Yuuya, Inoue, Masaki, Tsunoda, Shin-ichi, Shudo, Yoshie, Kurata, Takayasu, Obika, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527545/
https://www.ncbi.nlm.nih.gov/pubmed/31110284
http://dx.doi.org/10.1038/s41598-019-43100-1