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IL-1α promotes liver inflammation and necrosis during blood-stage Plasmodium chabaudi malaria

Malaria causes hepatic inflammation and damage, which contribute to disease severity. The pro-inflammatory cytokine interleukin (IL)-1α is released by non-hematopoietic or hematopoietic cells during liver injury. This study established the role of IL-1α in the liver pathology caused by blood-stage P...

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Detalles Bibliográficos
Autores principales: de Menezes, Maria Nogueira, Salles, Érika Machado, Vieira, Flávia, Amaral, Eduardo Pinheiro, Zuzarte-Luís, Vanessa, Cassado, Alexandra, Epiphanio, Sabrina, Alvarez, José Maria, Alves-Filho, José Carlos, Mota, Maria Manuel, D’Império-Lima, Maria Regina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527574/
https://www.ncbi.nlm.nih.gov/pubmed/31110285
http://dx.doi.org/10.1038/s41598-019-44125-2