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Senescence-related deterioration of intercellular junctions in the peritoneal mesothelium promotes the transmesothelial invasion of ovarian cancer cells

Mechanisms of transmesothelial invasion of ovarian cancer are still poorly understood. Here we examined whether this phenomenon may be determined by an expression of intercellular junctions in peritoneal mesothelial cells (PMCs). Analysis of ovarian tumors showed that cancer cells are localized belo...

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Detalles Bibliográficos
Autores principales: Pakuła, Martyna, Witucka, Anna, Uruski, Paweł, Radziemski, Artur, Moszyński, Rafał, Szpurek, Dariusz, Maksin, Konstantin, Woźniak, Aldona, Sajdak, Stefan, Tykarski, Andrzej, Mikuła-Pietrasik, Justyna, Książek, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527686/
https://www.ncbi.nlm.nih.gov/pubmed/31110245
http://dx.doi.org/10.1038/s41598-019-44123-4