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Constitutive alterations in vesicular trafficking increase the sensitivity of cells from celiac disease patients to gliadin

Celiac Disease (CD) is an autoimmune disease characterized by inflammation of the intestinal mucosa due to an immune response to wheat gliadins. Some gliadin peptides (e.g., A-gliadin P57-68) induce an adaptive Th1 pro-inflammatory response. Other gliadin peptides (e.g., A-gliadin P31-43) induce a s...

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Detalles Bibliográficos
Autores principales: Lania, Giuliana, Nanayakkara, Merlin, Maglio, Mariantonia, Auricchio, Renata, Porpora, Monia, Conte, Mariangela, De Matteis, Maria Antonietta, Rizzo, Riccardo, Luini, Alberto, Discepolo, Valentina, Troncone, Riccardo, Auricchio, Salvatore, Barone, Maria Vittoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527696/
https://www.ncbi.nlm.nih.gov/pubmed/31123714
http://dx.doi.org/10.1038/s42003-019-0443-1