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Methylation and PTEN activation in dental pulp mesenchymal stem cells promotes osteogenesis and reduces oncogenesis
Lineage commitment and tumorigenesis, traits distinguishing stem cells, have not been well characterized and compared in mesenchymal stem cells derived from human dental pulp (DP-MSCs) and bone marrow (BM-MSCs). Here, we report DP-MSCs exhibit increased osteogenic potential, possess decreased adipog...
Autores principales: | Shen, Wen-Ching, Lai, Yung-Chih, Li, Ling-Hui, Liao, Kolin, Lai, Hung-Chang, Kao, Shou-Yen, Wang, John, Chuong, Cheng-Ming, Hung, Shih-Chieh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527698/ https://www.ncbi.nlm.nih.gov/pubmed/31110221 http://dx.doi.org/10.1038/s41467-019-10197-x |
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