Cargando…

Methylation and PTEN activation in dental pulp mesenchymal stem cells promotes osteogenesis and reduces oncogenesis

Lineage commitment and tumorigenesis, traits distinguishing stem cells, have not been well characterized and compared in mesenchymal stem cells derived from human dental pulp (DP-MSCs) and bone marrow (BM-MSCs). Here, we report DP-MSCs exhibit increased osteogenic potential, possess decreased adipog...

Descripción completa

Detalles Bibliográficos
Autores principales: Shen, Wen-Ching, Lai, Yung-Chih, Li, Ling-Hui, Liao, Kolin, Lai, Hung-Chang, Kao, Shou-Yen, Wang, John, Chuong, Cheng-Ming, Hung, Shih-Chieh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527698/
https://www.ncbi.nlm.nih.gov/pubmed/31110221
http://dx.doi.org/10.1038/s41467-019-10197-x