FAK and Pyk2 activity promote TNF-α and IL-1β-mediated pro-inflammatory gene expression and vascular inflammation

Protein tyrosine kinase (PTK) activity has been implicated in pro-inflammatory gene expression following tumor necrosis factor-α (TNF-α) or interkeukin-1β (IL-1β) stimulation. However, the identity of responsible PTK(s) in cytokine signaling have not been elucidated. To evaluate which PTK is critica...

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Detalles Bibliográficos
Autores principales: Murphy, James M., Jeong, Kyuho, Rodriguez, Yelitza A. R., Kim, Jung-Hyun, Ahn, Eun-Young Erin, Lim, Ssang-Taek Steve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527705/
https://www.ncbi.nlm.nih.gov/pubmed/31110200
http://dx.doi.org/10.1038/s41598-019-44098-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527705/
https://www.ncbi.nlm.nih.gov/pubmed/31110200
http://dx.doi.org/10.1038/s41598-019-44098-2

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