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Phosphatidylcholine synthesis through cholinephosphate cytidylyltransferase is dispensable in Leishmania major

Phosphatidylcholine (PC) is a major cell membrane constituent and precursor of important second messengers. In Leishmania parasites, PC synthesis can occur via the choline branch of the Kennedy pathway, the N-methylation of phosphatidylethanolamine (PE), or the remodeling of exogenous phospholipids....

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Detalles Bibliográficos
Autores principales: Moitra, Samrat, Pawlowic, Mattie C., Hsu, Fong-fu, Zhang, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527706/
https://www.ncbi.nlm.nih.gov/pubmed/31110206
http://dx.doi.org/10.1038/s41598-019-44086-6