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Clinical utility of pembrolizumab in the management of advanced solid tumors: an evidence-based review on the emerging new data
Pembrolizumab is a full-length human immunoglobulin G4 (IgG4) monoclonal antibody directed against the immune checkpoint PD-1 to remove its binding with PD-L1 and thus to restore an anti-tumor immune response of T cells. Pembrolizumab is one of the most advanced immune checkpoint inhibitors for canc...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527794/ https://www.ncbi.nlm.nih.gov/pubmed/31190995 http://dx.doi.org/10.2147/CMAR.S151023 |