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hnRNPK S379 phosphorylation participates in migration regulation of triple negative MDA-MB-231 cells

We have previously identified a novel Aurora-A-mediated Serine 379 (S379) phosphorylation of a poly(C)-binding protein, hnRNPK, the overexpression of which is frequently observed in various cancers. It is known that the oncogenic Aurora-A kinase promotes the malignancy of cancer cells. This study ai...

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Detalles Bibliográficos
Autores principales: Tsai, Hsin-Yu, Fu, Shu-Ling, Tseng, Ling-Ming, Chiu, Jen-Hwey, Lin, Chao-Hsiung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527834/
https://www.ncbi.nlm.nih.gov/pubmed/31110205
http://dx.doi.org/10.1038/s41598-019-44063-z