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Long QT Syndrome Modelling with Cardiomyocytes Derived from Human-induced Pluripotent Stem Cells

Long QT syndrome (LQTS) is a potentially severe arrhythmogenic disorder, associated with a prolonged QT interval and sudden death, caused by mutations in key genes regulating cardiac electrophysiology. Current strategies to study LQTS in vitro include heterologous systems or animal models. Despite t...

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Detalles Bibliográficos
Autores principales: Sala, Luca, Gnecchi, Massimiliano, Schwartz, Peter J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Radcliffe Cardiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528025/
https://www.ncbi.nlm.nih.gov/pubmed/31114684
http://dx.doi.org/10.15420/aer.2019.1.1