Biocatalytic Detoxification of Paralytic Shellfish Toxins

[Image: see text] Small molecules that bind to voltage-gated sodium channels (VGSCs) are promising leads in the treatment of numerous neurodegenerative diseases and pain. Nature is a highly skilled medicinal chemist in this regard, designing potent VGSC ligands capable of binding to and blocking the...

Descripción completa

Detalles Bibliográficos
Autores principales: Lukowski, April L., Denomme, Nicholas, Hinze, Meagan E., Hall, Sherwood, Isom, Lori L., Narayan, Alison R. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528162/
https://www.ncbi.nlm.nih.gov/pubmed/30983320
http://dx.doi.org/10.1021/acschembio.9b00123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528162/
https://www.ncbi.nlm.nih.gov/pubmed/30983320
http://dx.doi.org/10.1021/acschembio.9b00123

Ejemplares similares