Cargando…

Low expression of SPARC in gastric cancer-associated fibroblasts leads to stemness transformation and 5-fluorouracil resistance in gastric cancer

BACKGROUND: The aim of the present study was to clarify the correlations between SPARC expression in gastric cancer-associated fibroblasts (GCAFs) and the prognosis of patients with gastric cancer and to elucidate the role of GCAF-derived SPARC in stemness transformation and 5-fluorouracil resistanc...

Descripción completa

Detalles Bibliográficos
Autores principales: Ma, Yongchen, Zhu, Jing, Chen, Shanwen, Ma, Ju, Zhang, Xiaoqian, Huang, Sixia, Hu, Jianwen, Yue, Taohua, Zhang, Junling, Wang, Pengyuan, Wang, Xin, Rong, Long, Guo, Hongjie, Chen, Guowei, Liu, Yucun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528188/
https://www.ncbi.nlm.nih.gov/pubmed/31139014
http://dx.doi.org/10.1186/s12935-019-0844-8