Genome analysis and pleiotropy assessment using causal networks with loss of function mutation and metabolomics

BACKGROUND: Many genome-wide association studies have detected genomic regions associated with traits, yet understanding the functional causes of association often remains elusive. Utilizing systems approaches and focusing on intermediate molecular phenotypes might facilitate biologic understanding....

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Detalles Bibliográficos
Autores principales: Yazdani, Azam, Yazdani, Akram, Elsea, Sarah H., Schaid, Daniel J., Kosorok, Michael R., Dangol, Gita, Samiei, Ahmad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528192/
https://www.ncbi.nlm.nih.gov/pubmed/31113383
http://dx.doi.org/10.1186/s12864-019-5772-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528192/
https://www.ncbi.nlm.nih.gov/pubmed/31113383
http://dx.doi.org/10.1186/s12864-019-5772-4

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