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R-spondin2 promotes hematopoietic differentiation of human pluripotent stem cells by activating TGF beta signaling
BACKGROUND: Human pluripotent stem cells (hPSCs) provide supplies of potential functional blood cells to suffice the clinical needs. However, the underlying mechanism of generating genuine hematopoietic stem cells (HSCs) and functional blood cells from hPSCs remains largely elusive. METHOD: In this...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528258/ https://www.ncbi.nlm.nih.gov/pubmed/31109354 http://dx.doi.org/10.1186/s13287-019-1242-9 |