Curcuminoid WZ35 synergize with cisplatin by inducing ROS production and inhibiting TrxR1 activity in gastric cancer cells

BACKGROUND: Cisplatin is one of the most widely used chemotherapeutic agents, but its efficacy is limited by its side effects. Hence, it is of great significance to develop novel agents to synergize with cisplatin and decrease side effects. In our previous study, we demonstrated that WZ35, a novel c...

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Detalles Bibliográficos
Autores principales: He, Wei, Xia, Yiqun, Cao, Peihai, Hong, Lin, Zhang, Tingting, Shen, Xin, Zheng, Peisen, Shen, Huanpei, Liang, Guang, Zou, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528260/
https://www.ncbi.nlm.nih.gov/pubmed/31113439
http://dx.doi.org/10.1186/s13046-019-1215-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528260/
https://www.ncbi.nlm.nih.gov/pubmed/31113439
http://dx.doi.org/10.1186/s13046-019-1215-y

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