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Diverse Isoquinoline Scaffolds by Ugi/Pomeranz–Fritsch and Ugi/Schlittler–Müller Reactions

[Image: see text] The Pomeranz–Fritsch reaction and its Schlittler–Müller modification were successfully applied in the Ugi postcyclization strategy by using orthogonally protected aminoacetaldehyde diethyl acetal and complementary electron rich building blocks. Several scaffolds, including isoquino...

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Detalles Bibliográficos
Autores principales: Wang, Yuanze, Patil, Pravin, Kurpiewska, Katarzyna, Kalinowska-Tluscik, Justyna, Dömling, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528277/
https://www.ncbi.nlm.nih.gov/pubmed/31033297
http://dx.doi.org/10.1021/acs.orglett.9b00778