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Preclinical evaluation of safety and potential of black hellebore extracts for cancer treatment

BACKGROUND: The therapeutic use of Helleborus niger L. is manifold due to its specific phytochemical composition. Two compound groups, the ranunculin derivates including protoanemonin and the steroidal saponins, are also associated with toxicity (genotoxicity, disintegration of membrane structures)....

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Detalles Bibliográficos
Autores principales: Felenda, Jennifer E., Turek, Claudia, Mörbt, Nora, Herrick, Anja, Müller, Margit B., Stintzing, Florian C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528284/
https://www.ncbi.nlm.nih.gov/pubmed/31113420
http://dx.doi.org/10.1186/s12906-019-2517-5