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Human embryonic stem cell-derived exosomes promote pressure ulcer healing in aged mice by rejuvenating senescent endothelial cells

BACKGROUND: Angiogenesis, as an endogenous repair mechanism, plays crucial roles in wound healing and tissue regeneration. However, this process is impaired in the elderly due to aging-related vascular endothelial dysfunction. This study was aimed to explore the pro-angiogenic effects of exosomes fr...

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Detalles Bibliográficos
Autores principales: Chen, Bi, Sun, Yongjin, Zhang, Juntao, Zhu, Qingwei, Yang, Yunlong, Niu, Xin, Deng, Zhifeng, Li, Qing, Wang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528288/
https://www.ncbi.nlm.nih.gov/pubmed/31113469
http://dx.doi.org/10.1186/s13287-019-1253-6