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Human embryonic stem cell-derived exosomes promote pressure ulcer healing in aged mice by rejuvenating senescent endothelial cells
BACKGROUND: Angiogenesis, as an endogenous repair mechanism, plays crucial roles in wound healing and tissue regeneration. However, this process is impaired in the elderly due to aging-related vascular endothelial dysfunction. This study was aimed to explore the pro-angiogenic effects of exosomes fr...
Autores principales: | Chen, Bi, Sun, Yongjin, Zhang, Juntao, Zhu, Qingwei, Yang, Yunlong, Niu, Xin, Deng, Zhifeng, Li, Qing, Wang, Yang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528288/ https://www.ncbi.nlm.nih.gov/pubmed/31113469 http://dx.doi.org/10.1186/s13287-019-1253-6 |
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