Susceptibility to L. sigmodontis infection is highest in animals lacking IL-4R/IL-5 compared to single knockouts of IL-4R, IL-5 or eosinophils

BACKGROUND: Mice are susceptible to infections with the rodent filarial nematode Litomosoides sigmodontis and develop immune responses that resemble those of human filarial infections. Thus, the L. sigmodontis model is used to study filarial immunomodulation, protective immune responses against fila...

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Detalles Bibliográficos
Autores principales: Frohberger, Stefan J., Ajendra, Jesuthas, Surendar, Jayagopi, Stamminger, Wiebke, Ehrens, Alexandra, Buerfent, Benedikt C., Gentil, Katrin, Hoerauf, Achim, Hübner, Marc P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528299/
https://www.ncbi.nlm.nih.gov/pubmed/31109364
http://dx.doi.org/10.1186/s13071-019-3502-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528299/
https://www.ncbi.nlm.nih.gov/pubmed/31109364
http://dx.doi.org/10.1186/s13071-019-3502-z

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