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Sigma-2 receptor/TMEM97 agonist PB221 as an alternative drug for brain tumor
BACKGROUND: There are limited effective drugs that can reach the brain to target brain tumors, in particular glioblastoma, which is one of the most difficult cancers to be cured from. Because the overexpression of the sigma-2 receptor is frequently reported in glioma clinical samples and associated...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528305/ https://www.ncbi.nlm.nih.gov/pubmed/31109310 http://dx.doi.org/10.1186/s12885-019-5700-7 |