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Sigma-2 receptor/TMEM97 agonist PB221 as an alternative drug for brain tumor

BACKGROUND: There are limited effective drugs that can reach the brain to target brain tumors, in particular glioblastoma, which is one of the most difficult cancers to be cured from. Because the overexpression of the sigma-2 receptor is frequently reported in glioma clinical samples and associated...

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Detalles Bibliográficos
Autores principales: Liu, Chia-Chi, Yu, Ching-Fang, Wang, Shu-Chi, Li, Hsueh-Yin, Lin, Chiu-Min, Wang, Hsia-Han, Abate, Carmen, Chiang, Chi-Shiun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528305/
https://www.ncbi.nlm.nih.gov/pubmed/31109310
http://dx.doi.org/10.1186/s12885-019-5700-7