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EGF and IGF1 affect sunitinib activity in BP-NEN: new putative targets beyond VEGFR?

Broncho-pulmonary neuroendocrine neoplasms (BP-NENs) are neoplasms orphan of an efficient therapy. Available medical treatments derived from clinical trials are not specific for the management of this malignancy. Sunitinib is a multi-receptor tyrosine-kinases (RTKs) inhibitor that has already shown...

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Detalles Bibliográficos
Autores principales: Bresciani, Giulia, Ditsiou, Angeliki, Cilibrasi, Chiara, Vella, Viviana, Rea, Federico, Schiavon, Marco, Cavallesco, Narciso Giorgio, Giamas, Georgios, Zatelli, Maria Chiara, Gagliano, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528406/
https://www.ncbi.nlm.nih.gov/pubmed/31035254
http://dx.doi.org/10.1530/EC-19-0192