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p53 mutation regulates PKD genes and results in co-occurrence of PKD and tumorigenesis
OBJECTIVE: Polycystic kidney disease (PKD) is the major cause of kidney failure and mortality in humans. It has always been suspected that the development of cystic kidney disease shares features with tumorigenesis, although the evidence is unclear. METHODS: We crossed p53 mutant mice (p53N236S, p53...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Chinese Anti-Cancer Association
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528458/ https://www.ncbi.nlm.nih.gov/pubmed/31119048 http://dx.doi.org/10.20892/j.issn.2095-3941.2018.0170 |