p53 mutation regulates PKD genes and results in co-occurrence of PKD and tumorigenesis

OBJECTIVE: Polycystic kidney disease (PKD) is the major cause of kidney failure and mortality in humans. It has always been suspected that the development of cystic kidney disease shares features with tumorigenesis, although the evidence is unclear. METHODS: We crossed p53 mutant mice (p53N236S, p53...

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Detalles Bibliográficos
Autores principales: Li, Haili, Zhang, Yongjin, Dan, Juhua, Zhou, Ruoyu, Li, Cui, Li, Rong, Wu, Xiaoming, Kumar Singh, Sanjay, T. Chang, Jeffrey, Yang, Julun, Luo, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Anti-Cancer Association 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528458/
https://www.ncbi.nlm.nih.gov/pubmed/31119048
http://dx.doi.org/10.20892/j.issn.2095-3941.2018.0170

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