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Non-clonal occurrence of pmrB mutations associated with polymyxin resistance in carbapenem-resistant Klebsiella pneumoniae in Brazil

BACKGROUND: Polymyxins are currently used as a “last-line” treatment for multidrug-resistant Gram-negative infections. OBJECTIVES: To identify the major mechanisms of resistance to polymyxin and compare the genetic similarity between multi-drug resistant Klebsiella pneumoniae strains recovered from...

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Detalles Bibliográficos
Autores principales: Rodrigues, Ana Claudia Souza, Santos, Ivson Cassiano de Oliveira, Campos, Caroline Conci, Rezende, Isadora Nascimento, Ferreira, Yanara Miranda, Chaves, Claudia Elisabeth Volpe, Rocha-de-Souza, Cláudio Marcos, Carvalho-Assef, Ana Paula D’Alincourt, Chang, Marilene Rodrigues
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528640/
https://www.ncbi.nlm.nih.gov/pubmed/31116243
http://dx.doi.org/10.1590/0074-02760180555