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BATF2 prevents T-cell-mediated intestinal inflammation through regulation of the IL-23/IL-17 pathway

Inappropriate activation of the IL-23 signaling pathway causes chronic inflammation through the induction of immunopathological T(h)17 cells in several tissues including the intestine, whereas adequate T(h)17 responses are essential for host defense against harmful organisms. In the intestinal lamin...

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Detalles Bibliográficos
Autores principales: Kayama, Hisako, Tani, Haruka, Kitada, Shoko, Opasawatchai, Anunya, Okumura, Ryu, Motooka, Daisuke, Nakamura, Shota, Takeda, Kiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528702/
https://www.ncbi.nlm.nih.gov/pubmed/30753547
http://dx.doi.org/10.1093/intimm/dxz014