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Anticonvulsant and ameliorative effects of pioglitazone on cognitive deficits, inflammation and apoptosis in the hippocampus of rat pups exposed to febrile seizure
OBJECTIVE(S): Pioglitazone (PGZ), a peroxisome proliferator-activated receptor gamma (PPAR-γ) agonist, has significant neuroprotective effects and has been reported to regulate inflammatory processes. MATERIALS AND METHODS: We evaluated the effects of PGZ on febrile seizure (FS) in rat pups. Three g...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Mashhad University of Medical Sciences
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528711/ https://www.ncbi.nlm.nih.gov/pubmed/31156787 http://dx.doi.org/10.22038/ijbms.2019.35056.8339 |