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Anti-diabetic effect of loganin by inhibiting FOXO1 nuclear translocation via PI3K/Akt signaling pathway in INS-1 cell

OBJECTIVE(S): JiangTangXiaoKe (JTXK) granule, a Chinese traditional herbal formula, has been clinically used and demonstrated to be beneficial in controlling high glucose and to relieve the symptoms of Type 2 diabetes mellitus patients for decades. In this study, we explored how loganin, one of the...

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Detalles Bibliográficos
Autores principales: Mo, Fang-Fang, Liu, Hai-Xia, Zhang, Yi, Hua, Jing, Zhao, Dan-Dan, An, Tian, Zhang, Dong-Wei, Tian, Tian, Gao, Si-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528715/
https://www.ncbi.nlm.nih.gov/pubmed/31156786
http://dx.doi.org/10.22038/ijbms.2019.30246.7294