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Evaluation of lentinan effects on cytochrome P450 activity in rats by a cocktail method
OBJECTIVE(S): In this study, a cocktail of probe drugs was used to assess whether lentinan could influence the activities of rat enzymes CYP3A4, CYP2D6, CYP1A2, CYP2C19, and CYP2C9 in vivo. MATERIALS AND METHODS: Fourteen days after intraperitoneal injection of lentinan, rats were given an oral dose...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mashhad University of Medical Sciences
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528719/ https://www.ncbi.nlm.nih.gov/pubmed/31156791 http://dx.doi.org/10.22038/ijbms.2019.31611.7611 |