Regulation of membrane phospholipid asymmetry by Notch-mediated flippase expression controls the number of intraepithelial TCRαβ(+)CD8αα(+) T cells

Intestinal intraepithelial lymphocytes (IELs) expressing CD8αα on αβ T cells (TCRαβ(+)CD8αα(+) IELs) have suppressive capabilities in enterocolitis, but the mechanism that maintains homeostasis and cell number is not fully understood. Here, we demonstrated that the number of TCRαβ(+)CD8αα(+) IELs wa...

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Detalles Bibliográficos
Autores principales: Ishifune, Chieko, Tsukumo, Shin-ichi, Maekawa, Yoichi, Hozumi, Katsuto, Chung, Doo Hyun, Motozono, Chihiro, Yamasaki, Sho, Nakano, Hiroyasu, Yasutomo, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529014/
https://www.ncbi.nlm.nih.gov/pubmed/31071093
http://dx.doi.org/10.1371/journal.pbio.3000262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529014/
https://www.ncbi.nlm.nih.gov/pubmed/31071093
http://dx.doi.org/10.1371/journal.pbio.3000262

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