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The knob protein KAHRP assembles into a ring-shaped structure that underpins virulence complex assembly

Plasmodium falciparum mediates adhesion of infected red blood cells (RBCs) to blood vessel walls by assembling a multi-protein complex at the RBC surface. This virulence-mediating structure, called the knob, acts as a scaffold for the presentation of the major virulence antigen, P. falciparum Erythr...

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Detalles Bibliográficos
Autores principales: Looker, Oliver, Blanch, Adam J., Liu, Boyin, Nunez-Iglesias, Juan, McMillan, Paul J., Tilley, Leann, Dixon, Matthew W. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529015/
https://www.ncbi.nlm.nih.gov/pubmed/31071194
http://dx.doi.org/10.1371/journal.ppat.1007761