A streptococcal Fic domain-containing protein disrupts blood-brain barrier integrity by activating moesin in endothelial cells

Streptococcus equi subsp. zooepidemicus (SEZ) is a zoonotic pathogen capable of causing meningitis in humans. The mechanisms that enable pathogens to traverse the blood-brain barrier (BBB) are incompletely understood. Here, we investigated the role of a newly identified Fic domain-containing protein...

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Detalles Bibliográficos
Autores principales: Ma, Zhe, Peng, Jie, Yu, Dandan, Park, Joseph S., Lin, Huixing, Xu, Bin, Lu, Chengping, Fan, Hongjie, Waldor, Matthew K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529018/
https://www.ncbi.nlm.nih.gov/pubmed/31071198
http://dx.doi.org/10.1371/journal.ppat.1007737

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529018/
https://www.ncbi.nlm.nih.gov/pubmed/31071198
http://dx.doi.org/10.1371/journal.ppat.1007737

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