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A streptococcal Fic domain-containing protein disrupts blood-brain barrier integrity by activating moesin in endothelial cells
Streptococcus equi subsp. zooepidemicus (SEZ) is a zoonotic pathogen capable of causing meningitis in humans. The mechanisms that enable pathogens to traverse the blood-brain barrier (BBB) are incompletely understood. Here, we investigated the role of a newly identified Fic domain-containing protein...
Autores principales: | Ma, Zhe, Peng, Jie, Yu, Dandan, Park, Joseph S., Lin, Huixing, Xu, Bin, Lu, Chengping, Fan, Hongjie, Waldor, Matthew K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529018/ https://www.ncbi.nlm.nih.gov/pubmed/31071198 http://dx.doi.org/10.1371/journal.ppat.1007737 |
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