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Mitochondria P-glycoprotein confers paclitaxel resistance on ovarian cancer cells

Background: Subcellular expression of P-glycoprotein (P-gp) may play an essential role in multidrug resistance (MDR) in many cancers. However, the mitochondria expression and functional activity of P-gp in ovarian cancer are still unclear. In this study, we isolated mitochondria from A2780 cell line...

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Detalles Bibliográficos
Autores principales: Guo, Weina, Dong, Weihong, Li, Min, Shen, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529025/
https://www.ncbi.nlm.nih.gov/pubmed/31190887
http://dx.doi.org/10.2147/OTT.S193433