Translation affects mRNA stability in a codon-dependent manner in human cells

mRNA translation decodes nucleotide into amino acid sequences. However, translation has also been shown to affect mRNA stability depending on codon composition in model organisms, although universality of this mechanism remains unclear. Here, using three independent approaches to measure exogenous a...

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Detalles Bibliográficos
Autores principales: Wu, Qiushuang, Medina, Santiago Gerardo, Kushawah, Gopal, DeVore, Michelle Lynn, Castellano, Luciana A, Hand, Jacqelyn M, Wright, Matthew, Bazzini, Ariel Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529216/
https://www.ncbi.nlm.nih.gov/pubmed/31012849
http://dx.doi.org/10.7554/eLife.45396

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529216/
https://www.ncbi.nlm.nih.gov/pubmed/31012849
http://dx.doi.org/10.7554/eLife.45396

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