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MicroRNA-deficient mouse embryonic stem cells acquire a functional interferon response
When mammalian cells detect a viral infection, they initiate a type I interferon (IFNs) response as part of their innate immune system. This antiviral mechanism is conserved in virtually all cell types, except for embryonic stem cells (ESCs) and oocytes which are intrinsically incapable of producing...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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eLife Sciences Publications, Ltd
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529217/ https://www.ncbi.nlm.nih.gov/pubmed/31012846 http://dx.doi.org/10.7554/eLife.44171 |