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Inorganic nitrate, hypoxia, and the regulation of cardiac mitochondrial respiration—probing the role of PPARα

Dietary inorganic nitrate prevents aspects of cardiac mitochondrial dysfunction induced by hypoxia, although the mechanism is not completely understood. In both heart and skeletal muscle, nitrate increases fatty acid oxidation capacity, and in the latter case, this involves up-regulation of peroxiso...

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Detalles Bibliográficos
Autores principales: Horscroft, James A., O’Brien, Katie A., Clark, Anna D., Lindsay, Ross T., Steel, Alice Strang, Procter, Nathan E. K., Devaux, Jules, Frenneaux, Michael, Harridge, Stephen D. R., Murray, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529343/
https://www.ncbi.nlm.nih.gov/pubmed/30870003
http://dx.doi.org/10.1096/fj.201900067R