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Inorganic nitrate, hypoxia, and the regulation of cardiac mitochondrial respiration—probing the role of PPARα
Dietary inorganic nitrate prevents aspects of cardiac mitochondrial dysfunction induced by hypoxia, although the mechanism is not completely understood. In both heart and skeletal muscle, nitrate increases fatty acid oxidation capacity, and in the latter case, this involves up-regulation of peroxiso...
Autores principales: | Horscroft, James A., O’Brien, Katie A., Clark, Anna D., Lindsay, Ross T., Steel, Alice Strang, Procter, Nathan E. K., Devaux, Jules, Frenneaux, Michael, Harridge, Stephen D. R., Murray, Andrew J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Federation of American Societies for Experimental Biology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529343/ https://www.ncbi.nlm.nih.gov/pubmed/30870003 http://dx.doi.org/10.1096/fj.201900067R |
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