The extracellular gate shapes the energy profile of an ABC exporter

ABC exporters harness the energy of ATP to pump substrates across membranes. Extracellular gate opening and closure are key steps of the transport cycle, but the underlying mechanism is poorly understood. Here, we generated a synthetic single domain antibody (sybody) that recognizes the heterodimeri...

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Detalles Bibliográficos
Autores principales: Hutter, Cedric A. J., Timachi, M. Hadi, Hürlimann, Lea M., Zimmermann, Iwan, Egloff, Pascal, Göddeke, Hendrik, Kucher, Svetlana, Štefanić, Saša, Karttunen, Mikko, Schäfer, Lars V., Bordignon, Enrica, Seeger, Markus A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529423/
https://www.ncbi.nlm.nih.gov/pubmed/31113958
http://dx.doi.org/10.1038/s41467-019-09892-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529423/
https://www.ncbi.nlm.nih.gov/pubmed/31113958
http://dx.doi.org/10.1038/s41467-019-09892-6

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