Prosurvival autophagy is regulated by protein kinase CK1 alpha in multiple myeloma

Multiple myeloma (MM) is a tumor of plasma cells (PCs). Due to the intense immunoglobulin secretion, PCs are prone to endoplasmic reticulum stress and activate several stress-managing pathways, including autophagy. Indeed, autophagy deregulation is maladaptive for MM cells, resulting in cell death....

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Detalles Bibliográficos
Autores principales: Carrino, Marilena, Quotti Tubi, Laura, Fregnani, Anna, Canovas Nunes, Sara, Barilà, Gregorio, Trentin, Livio, Zambello, Renato, Semenzato, Gianpietro, Manni, Sabrina, Piazza, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529432/
https://www.ncbi.nlm.nih.gov/pubmed/31123604
http://dx.doi.org/10.1038/s41420-019-0179-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529432/
https://www.ncbi.nlm.nih.gov/pubmed/31123604
http://dx.doi.org/10.1038/s41420-019-0179-1

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