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Estrogen negatively regulates the renal epithelial sodium channel (ENaC) by promoting Derlin-1 expression and AMPK activation

The main functions of the epithelial sodium channel (ENaC) in the kidney distal nephron are mediation of sodium and water balance and stabilization of blood pressure. Estrogen has important effects on sodium and water balance and on premenopausal blood pressure, but its role in the regulation of ENa...

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Detalles Bibliográficos
Autores principales: Zhang, Xue, Ge, Yamei, Bukhari, Ashfaq-Ahmad-Shah, Zhu, Qian, Shen, Yachen, Li, Min, Sun, Hui, Su, Dongming, Liang, Xiubin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529463/
https://www.ncbi.nlm.nih.gov/pubmed/31113930
http://dx.doi.org/10.1038/s12276-019-0253-z