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Estrogen negatively regulates the renal epithelial sodium channel (ENaC) by promoting Derlin-1 expression and AMPK activation
The main functions of the epithelial sodium channel (ENaC) in the kidney distal nephron are mediation of sodium and water balance and stabilization of blood pressure. Estrogen has important effects on sodium and water balance and on premenopausal blood pressure, but its role in the regulation of ENa...
Autores principales: | Zhang, Xue, Ge, Yamei, Bukhari, Ashfaq-Ahmad-Shah, Zhu, Qian, Shen, Yachen, Li, Min, Sun, Hui, Su, Dongming, Liang, Xiubin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529463/ https://www.ncbi.nlm.nih.gov/pubmed/31113930 http://dx.doi.org/10.1038/s12276-019-0253-z |
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