MeHg-induced autophagy via JNK/Vps34 complex pathway promotes autophagosome accumulation and neuronal cell death

Methylmercury (MeHg), an environmental toxin, may specifically cause neurological disorders. Recent studies have reported that autophagy can be induced by metals and be involved in metal cytotoxicity. However, the role of autophagy in MeHg-induced neurotoxicity remains unknown. Here, we demonstrate...

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Detalles Bibliográficos
Autores principales: Lin, Tianji, Ruan, Shijuan, Huang, Dingbang, Meng, Xiaojing, Li, Wenjun, Wang, Bin, Zou, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529499/
https://www.ncbi.nlm.nih.gov/pubmed/31113939
http://dx.doi.org/10.1038/s41419-019-1632-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529499/
https://www.ncbi.nlm.nih.gov/pubmed/31113939
http://dx.doi.org/10.1038/s41419-019-1632-z

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