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MeHg-induced autophagy via JNK/Vps34 complex pathway promotes autophagosome accumulation and neuronal cell death
Methylmercury (MeHg), an environmental toxin, may specifically cause neurological disorders. Recent studies have reported that autophagy can be induced by metals and be involved in metal cytotoxicity. However, the role of autophagy in MeHg-induced neurotoxicity remains unknown. Here, we demonstrate...
Autores principales: | Lin, Tianji, Ruan, Shijuan, Huang, Dingbang, Meng, Xiaojing, Li, Wenjun, Wang, Bin, Zou, Fei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529499/ https://www.ncbi.nlm.nih.gov/pubmed/31113939 http://dx.doi.org/10.1038/s41419-019-1632-z |
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