Purinergic Signaling and Aminoglycoside Ototoxicity: The Opposing Roles of P1 (Adenosine) and P2 (ATP) Receptors on Cochlear Hair Cell Survival

Purinergic signaling regulates important physiological processes and the homeostatic response to stress in the cochlea via extracellular nucleosides (adenosine) and nucleotides (ATP, UTP). Using a previously established organotypic culture model, the current study investigated the effect of purinerg...

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Detalles Bibliográficos
Autores principales: Lin, Shelly C. Y., Thorne, Peter R., Housley, Gary D., Vlajkovic, Srdjan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529511/
https://www.ncbi.nlm.nih.gov/pubmed/31156393
http://dx.doi.org/10.3389/fncel.2019.00207

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529511/
https://www.ncbi.nlm.nih.gov/pubmed/31156393
http://dx.doi.org/10.3389/fncel.2019.00207

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