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Purinergic Signaling and Aminoglycoside Ototoxicity: The Opposing Roles of P1 (Adenosine) and P2 (ATP) Receptors on Cochlear Hair Cell Survival
Purinergic signaling regulates important physiological processes and the homeostatic response to stress in the cochlea via extracellular nucleosides (adenosine) and nucleotides (ATP, UTP). Using a previously established organotypic culture model, the current study investigated the effect of purinerg...
Autores principales: | Lin, Shelly C. Y., Thorne, Peter R., Housley, Gary D., Vlajkovic, Srdjan M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529511/ https://www.ncbi.nlm.nih.gov/pubmed/31156393 http://dx.doi.org/10.3389/fncel.2019.00207 |
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