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Variable Baseline Papio cynocephalus Endogenous Retrovirus (PcEV) Expression Is Upregulated in Acutely SIV-Infected Macaques and Correlated to STAT1 Expression in the Spleen

Retroviral replication leaves a DNA copy in the host cell chromosome, which over millions of years of infection of germline cells has led to 5% of the human genome sequence being comprised of endogenous retroviruses (ERVs), distributed throughout an estimated 100,000 loci. Over time these loci have...

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Detalles Bibliográficos
Autores principales: Maze, Emmanuel Atangana, Ham, Claire, Kelly, Jack, Ussher, Lindsay, Almond, Neil, Towers, Greg J., Berry, Neil, Belshaw, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529565/
https://www.ncbi.nlm.nih.gov/pubmed/31156613
http://dx.doi.org/10.3389/fimmu.2019.00901