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Perturbation of Thymocyte Development Underlies the PRRS Pandemic: A Testable Hypothesis

Porcine reproductive and respiratory syndrome virus (PRRSV) causes immune dysregulation during the Critical Window of Immunological Development. We hypothesize that thymocyte development is altered by infected thymic antigen presenting cells (TAPCs) in the fetal/neonatal thymus that interact with do...

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Detalles Bibliográficos
Autores principales: Butler, John E., Sinkora, Marek, Wang, Gang, Stepanova, Katerina, Li, Yuming, Cai, Xuehui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529568/
https://www.ncbi.nlm.nih.gov/pubmed/31156633
http://dx.doi.org/10.3389/fimmu.2019.01077